Alkyl Halides
Medchemexpress LLC Bromo-PEG3-bromide | 31255-26-2 | 98.8% | C8H16Br2O3 | 250 MG
Bromo-PEG3-bromide is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are compounds designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Contains two distinct ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other ligand targets a protein of interest
- Leverages the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Bromo-PEG3-bromide | 31255-26-2 | 98.8% | C8H16Br2O3 | 1 G
Bromo-PEG3-bromide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs.
- It is a PEG-based PROTAC linker.
- For research use only.
Medchemexpress LLC 2-Methylpropane-2-sulfinamide | 146374-27-8 | 98.0% | 121.20 | 500 G
2-Methylpropane-2-sulfinamide is an amide compound utilized as an intermediate in pharmaceutical synthesis. It is employed in the synthesis of 4-sulfonimidoylpiperidine and reacts with benzyl Grignard reagent to produce 4-benzyl-4-aminopiperidine, which is a significant pharmaceutical building block. Additionally, it can be used to insert a methylene group into derivatized sulfonimides for the creation of spiro-tosylaziridines.
- Used as an intermediate in pharmaceutical synthesis.
- Employed in the synthesis of 4-sulfonimidoylpiperidine.
- Reacts with benzyl Grignard reagent to produce 4-benzyl-4-aminopiperidine.
- Can be used to insert a methylene group into derivatized sulfonimides for the creation of spiro-tosylaziridines.
eMolecules Methyl 4-bromo-3-(bromomethyl)benzoate | 142031-67-2 | MFCD11858300 | 1g
Ambeed | Methyl 4-bromo-3-(bromomethyl)benzoate | 1g | 525143793 | A235223 | | 142031-67-2 | MFCD11858300 | 307.969 | C9H8Br2O2
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Matrix Scientific 1-BROMONONANE-25G
1-Bromononane, 98%; 25g,C9H19Br, MFCD00000278, mw 207.16, [693-58-3]
Chem-Impex International, Inc. Ethyl 5-bromovalerate | 14660-52-7 | MFCD00000266 | 5G
Ethyl 5-bromovalerate, 14660-52-7, MFCD00000266, 5G
Cambridge Isotope Laboratories 2 9L Aluminum cylinder with brass CGA 350 valve ea
2 9L Aluminum cylinder with brass CGA 350 valve ea
Medchemexpress LLC Bis(2-bromoethyl) ether | 5414-19-7 | 99.8% | 231.92 | 25 G
Bis(2-bromoethyl) ether is an alkyl chain-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs themselves consist of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules function by harnessing the intracellular ubiquitin-proteasome system to achieve the selective degradation of target proteins.
- It is an alkyl chain-based linker.
- It can be used in the synthesis of PROTACs.
- The linked PROTACs exploit the intracellular ubiquitin-proteasome system.
- The linked PROTACs selectively degrade target proteins.
Medchemexpress LLC 1-Bromotetradecane-d29 | 347841-80-9 | 98.4% | 306.46 | 1 MG
1-Bromotetradecane-d29 is the deuterium labeled 1-Bromotetradecane. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process. Deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
![eMolecules Ambeed / trans-Cyclohexane-12-dicarboxylic acid / 5g / 552534526 / A112867 / / 2305-32-0 / [null] / 344.360 / C16H24O8](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502424707.PNG-250.jpg)
eMolecules Ambeed / trans-Cyclohexane-12-dicarboxylic acid / 5g / 552534526 / A112867 / / 2305-32-0 / [null] / 344.360 / C16H24O8
Ambeed / trans-Cyclohexane-12-dicarboxylic acid / 5g / 552534526 / A112867 / / 2305-32-0 / [null] / 344.360 / C16H24O8
Medchemexpress LLC Bromo-PEG3-bromide | 31255-26-2 | MFCD18205853 | 98.8% | C8H16Br2O3 | 5 G
Bromo-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Bromo-PEG8-bromide | 2376383-09-2 | 98.0% | 540.28 g/mol | C18H36Br2O8 | 1 G
Bromo-PEG8-bromide is a bifunctional polyethylene glycol (PEG) linker bearing terminal bromide groups on both ends. It is a hydrophilic spacer useful for nucleophilic substitution reactions and bioconjugation in drug-delivery research and linker synthesis for antibody-drug conjugates and PROTACs. Molecular formula C18H36Br2O8, molecular weight 540.28 g/mol, CAS 2376383-09-2.
- Bifunctional PEG linker with terminal bromide groups for facile nucleophilic substitution.
- Enhances solubility and flexibility of conjugates in aqueous media.
- Suitable for bioconjugation and linker synthesis in drug-delivery research.
- Useful for constructing linkers in ADC and PROTAC workflows.
- Typically supplied as a liquid for straightforward handling.
Medchemexpress LLC (±)-WB 4101 hydrochloride | 2170-58-3 | 97.1% | 25 MG
(±)-WB 4101 hydrochloride is a potent and highly selective α1-adrenergic receptor antagonist. It interacts with proteins in smooth muscle, blocking norepinephrine-induced vascular smooth muscle contraction.
- Potent antagonist of noradrenaline
- Interacts with proteins in smooth muscle
- Makes drug and receptor bind tightly
- Highly selective α1-adrenergic receptor antagonist
- Exerts antihypertensive effects
- Provides benign prostatic hyperplasia (BPH)-relieving effects
- Promising for research of hypertension
- Promising for research of benign prostatic hyperplasia (BPH)
Medchemexpress LLC (±)-WB 4101 hydrochloride | 2170-58-3 | 97.1% | 10 MM * 1 ML
(±)-WB 4101 hydrochloride is a potent antagonist of noradrenaline. It interacts with protein in smooth muscle, promoting tight binding between the drug and receptor.
- Potent antagonist of noradrenaline
- Interacts with protein in smooth muscle
- Promotes tight binding between the drug and receptor
- Store solid form at -20°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
Medchemexpress LLC 1-Bromopentadecane-1 100mg
1-Bromopentadecane-1-13C is the 13C labeled 1-Bromopentadecane[1]